TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 31.6nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 31.6nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 50.1nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 79.4nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 398nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 631nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 631nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 631nMAssay Description:Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assayMore data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: <740nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 760nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 780nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 810nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 830nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 840nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 860nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 870nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 890nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 910nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 910nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 940nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 990nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair
TargetPEX5-related protein/Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:20 nM ofGST-tagged HCNlc40 protein (corresponding to the C terminal 40 amino acids of HCN1) was incubated with 200 nM of His-tagged TRIP8b(241-602) a...More data for this Ligand-Target Pair